People Can Lose Their Zest for Life After Starting GLP 1s, Docs Warn The rise of GLP 1 medications like semaglutide (Wegovy and Ozempic) and tirzepatide (Zepbound and Mounjaro) has been a game changer for millions struggling with obesity.
These pills have helped people shed pounds, reduced their cravings for food, decreased unhealthy urges for addictive vices like alcohol and gambling, and even shown promise as treatments for substance use disorders.
However, a new warning from doctors highlights a disturbing side effect: that GLP 1s may be altering the brain's reward system in ways that can have unintended consequences.